Case 13

June 30, 2020

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Patient #13, a 10-year-old female diagnosed with cystic fibrosis, who was admitted to the hospital for CF exacerbation with an Achromobacter xylosidans infection resistant to all available antibiotics. The patient was initially treated with the experimental antibiotic cefiderocol and 17 days later she began her phage therapy. During the first 5 days of phage therapy, […]

Case 11

June 30, 2020

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Patient #11, a 23-year-old male with cystic fibrosis who developed a multidrug resistant Burkholderia gladioli infection in his chest cavity prior to a lung transplant in 2017. Since the transplant, the patient suffered from a sternal wound infection and recurrent bacteremia caused by the same bacterial pathogen. Phage therapy was initiated in early November 2018. The doctor reported marked clinical […]

Case 8

June 30, 2020

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Patient #8, a 28-year-old female with cystic fibrosis who developed a multidrug resistant Burkholderia dolosa infection in her lungs after having a bilateral lung transplant in early 2018. Despite multiple courses of antibiotics, the patient continued to deteriorate. Phage therapy was initiated in early September and additional doses were supplied in mid-September and early October. The patient’s bacterial […]

Case 5

June 30, 2020

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Patient #5, a 25 year old female with cystic fibrosis. She had a long history of multidrug resistant Burkholderia cenocepacia in her sputum. Despite her history, she was able to find a surgeon willing to perform a double lung transplant. Her post-transplant course was complicated by a re-emergence of the multidrug resistant Burkholderia cenocepacia in her […]

Case 4

June 30, 2020

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Patient #4, a 67 year old male with a history of hypersensitivity pneumonitis and pulmonary fibrosis. He underwent bilateral lung transplantation in October 2016. His post-transplant course was complicated, including the development of two episodes of multidrug resistant Pseudomonas aeruginosa pneumonia. Bacteriophage therapy was administered via nebulizer and intravenously, along with adjunctive systemic antibiotics. Therapy […]