Case 22

June 30, 2020

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Pateint #22, a 69 year-old woman with a past medical history of chronic kidney disease, hypothyroidism, severe congestive heart failure with reduced ejection fraction, prosthetic knee joint infection, and a history of bacteremia. In November 2016, she had a left ventricular assist device (LVAD) placed and a right knee arthroplasty. Over a 4 year period […]

Case 21

June 30, 2020

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Patient #21, a 69 year-old male with a history of ischemic heart disease and non-insulin-dependent diabetes mellitus.  He was admitted in November 2019 with malignant otitis and mastoiditis on his left ear due to Pseudomonas aeruginosa. The patient was discharged on Dec 1st and readmitted with the same issue on Dec 8th suggesting failure on antibiotics.  On Dec 19th, he had […]

Case 20

June 30, 2020

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Patient #20 was a 10 year-old female with an inherited genetic dilated cardiomyopathy and had a Berlin heart inserted in January 2019. She had a prolonged hospital course that included colonization with Klebsiella pneumoniae and Pseudomonas aeruginosa, Clostridum difficile toxin-associated colitis and almost persistent bacteremia with P. aeruginosa. She recieved seven weeks of a single […]

Case 19

June 30, 2020

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Patient #19, a 7-year-old female who sustained multiple injuries from a MVA in 2018. This accident led to a long hospital admission and multiple surgical interventions with metal hardware (bilaterally, from hips down) ultimately resulting in chronic multidrug resistant P. aeruginosa osteomyelitis of the left foot. Her physicians sought out phage therapy since futher surgery […]

Case 15

June 30, 2020

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Patient #15, a 46-year-old male who had multiple trauma 25 years ago during his service in the military. During this time, he had multiple prolonged admissions to the hospital where he eventually developed Pseudomonas aeruginosa osteomyletis in his left tibia. The most recent imaging at the site of infection suggested that the P. aeruginosa had […]

Case 6

June 30, 2020

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Patient #6, a 60 year old male with a left ventricular assist device infected with multidrug resistant Pseudomonas aeruginosa. His blood cultures were positive. He received 6 weeks of an intravenous bacteriophage mixture containing three phage. Phage was provided to the patient in four shipments. Drainage from the device became significantly less, and the patient […]

Case 4

June 30, 2020

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Patient #4, a 67 year old male with a history of hypersensitivity pneumonitis and pulmonary fibrosis. He underwent bilateral lung transplantation in October 2016. His post-transplant course was complicated, including the development of two episodes of multidrug resistant Pseudomonas aeruginosa pneumonia. Bacteriophage therapy was administered via nebulizer and intravenously, along with adjunctive systemic antibiotics. Therapy […]

Case 2

June 16, 2020

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Patient #2, a 2 year old male with a history of DiGeorge Syndrome and complex congenital heart disease. Following cardiac surgery, he developed a recalcitrant multidrug resistant Pseudomonas aeruginosa bacteremia. Bacteriophage therapy was initiated intravenously, but then held due to progressive heart failure. Despite premature cessation of therapy, blood cultures obtained 4 and 5 days […]